TISSUE MICROARRAYS (TMAs) AVAILABLE TO CHTN INVESTIGATORS

The Mid-Atlantic Division (http://faculty.virginia.edu/chtn-tma/home.html) currently has the following TMAs available to CHTN investigators. All unstained histologic sections are 4 microns thick on charged glass slides.

• Normal Human Tissues TMA
• Test TMA
• Colorectal Carcinoma Progression TMA
• Human Nervous System TMA
• Breast Cancer Progression TMA
• Ovarian Carcinoma Survey

The Pediatric Division houses the Children’s Oncology Group (COG) Solid Tumor Tissue Bank, one of the two COG Acute Lymphoblastic Leukemia banks and the Gynecologic Oncology Group (GOG) Tissue Bank. Both the COG and GOG have created tissue microarrays, which are available to CHTN investigators.

CHTN investigators have access to the following COG TMAs which have one to four 1.0 mm cores per block taken from each case that are distributed randomly throughout the block.

• Alveolar Rhabdoymosarcoma array
• Embryonal Rhabdomyosarcoma array
• Osteosarcoma (Therapeutic) array
• Low Grade Glioma array
• Malignant Rhabdoid Tumor array
• Wilms’ Tumor (Stage III ,Therapeutic) array
• Wilms’ Tumor (all stages) array
• Medulloblastoma array
• Ewing’s Sarcoma (Therapeutic) array
• Ewing’s Sarcoma (Biology) array
• Neuroblastoma array

CHTN investigators also have access to the following GOG TMAs created utilizing a 0.6 mm core.

• Ovarian Disease Progress array
• Ovarian Stage Progression array
• Ovarian Histologic Subtype array

For more information on any of the TMAs listed above, please contact the Mid-Atlantic Division (434-982-6453) or the Pediatric Division (614-722-2714).

Last updated: 10/16/07. for comments or concerns about this web site please contact: Steve Marroulis at tissueresources@imsweb.com